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The Ghana Climate Innovation Centre (GCIC) is a pioneering business incubator and accelerator with a unique focus on supporting small and medium-sized enterprises (SMEs) in Ghana’s ‘Green Economy’. The Centre is an institute of Ashesi University, one of Africa’s leading liberal arts universities with a mission to raise ethical, entrepreneurial leaders with the courage to transform the continent. GCIC’s work is at the nexus of private enterprise, climate change, economic development, and ecological prosperity. We support an exceptional set of transformational businesses and entrepreneurs who are pioneering adaptive and mitigating solutions for climate change issues in Ghana. Since the commencement of business incubation activities in June 2017, GCIC has supported 197 enterprises in Ghana’s small and growing business sector that have climate innovation in six key economic sectors, namely: climate-smart agriculture, solar power, energy efficiency, domestic waste management, greening and water management and purification. To date, these enterprises have performed admirably to, inter alia, scale their businesses, generating cumulative revenue of over US$61.3m, sequestered 3m MTs of CO2 emissions, raised additional capital of over US$42.6m, created total employment of 30,617, and served over 30.2 million customers with green goods and services.